InhaltsangabePreface. List of Contributors. 1. Why RNA? J. Barciszewski, B.F.C. Clark. 2. Algorithms and thermodynamics for RNA secondary structure prediction: a practical guide; M. Zuker, et al. 3. Recurrent RNA motifs: Analysis at the basepair level; N.B. Leontis, E. Westhof. 4. Towards the 3D structure of 5S rRNA; M. Perbandt, et al. 5. Structure and dynamics of adenosine loops in RNA bulge duplexes. RNA hydration at the bulge site; L. Bielecki, et al. 6. The structure and function of the ribozyme RNAse P RNA is dictated by magnesium(II) ions; L. Kirsebom. 7. Metal ion-induced cleavages in probing of RNA structure; J. Ciesiotko. 8. Protein-DNA recognition; D. Rhodes. 9. Specific interaction between damaged bases in DNA and repair enzymes; K. Morikawa. 10. Telomeric DNA recognition; D. Rhodes. 11. Recognition of one tRNA by two classes of aminoacyl-tRNA synthetase; M. Ibba, et al. 12. Functional structures of class-I-aminoacyl-tRNA synthetases; O. Nureki, et al. 13. Aminoacylation of tRNA induces a conformational switch on the 3'-terminal ribose; A. Schlosser, et al. 14. Point mutants of elongation factor Tu from E. coli impaired in binding aminoaycl-tRNA; C.R. Knudsen, et al. 15. RNA structure and RNA-protein recognition during regulation of eukaryotic gene expression; G. Varani, et al. 16. RNA-aptamers for studying RNA-protein interactions; M. Sprinzl, et al. 17. Probing of ribonucleoprotein complexes with site-specifically derivatized RNAs; M.M. Konarska, et al. 18. The IRE model for families of RNA structures: Selective recognition by binding proteins (IRPs), NMR spectroscopy and probing with metal coordination complexes; E.C. Theil, et al. 19. Functional analysis of RNA signals in the HIV-1 genome by forced evolution; B. Berkhout, A.T. Das. 20. Interaction of native RNAs with Tat peptides; E. Wyszko, et al. 21. Biogenesis, structure and function of small nucleolar RNAs; W. Filipowicz, et al. 22. RNA structure modules with trinucleotide repeat motifs; W. Krzyzosiak, et al. 23. Phosphorothioate oligonucleotides as aptamers of retroviral reverse transcriptases; M. Koziotkiewicz, et al. 24. Oxathiaphospholane method of the stereocontrolled cynthesis of phosphorothioate analogues of oligonucleotides; A. Okruszek. 25. Towards improved applications of cell-free protein biosynthesis &endash; the influence of mRNA structure and suppressor tRNAs on the efficiency of the system; M. Gerrits, et al. 26. RNA on the web; M. Szymański, et al. 27. How risky is direct democracy for basic science? P. Mani. Subject Index.

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Preface. List of Contributors. 1. Why RNA? J. Barciszewski, B.F.C. Clark. 2. Algorithms and thermodynamics for RNA secondary structure prediction: a practical guide; M. Zuker, et al. 3. Recurrent RNA motifs: Analysis at the basepair level; N.B. Leontis, E. Westhof. 4. Towards the 3D structure of 5S rRNA; M. Perbandt, et al. 5. Structure and dynamics of adenosine loops in RNA bulge duplexes. RNA hydration at the bulge site; L. Bielecki, et al. 6. The structure and function of the ribozyme RNAse P RNA is dictated by magnesium(II) ions; L. Kirsebom. 7. Metal ion-induced cleavages in probing of RNA structure; J. Ciesiotko. 8. Protein-DNA recognition; D. Rhodes. 9. Specific interaction between damaged bases in DNA and repair enzymes; K. Morikawa. 10. Telomeric DNA recognition; D. Rhodes. 11. Recognition of one tRNA by two classes of aminoacyl-tRNA synthetase; M. Ibba, et al. 12. Functional structures of class-I-aminoacyl-tRNA synthetases; O. Nureki, et al. 13. Aminoacylation of tRNA induces a conformational switch on the 3''-terminal ribose; A. Schlosser, et al. 14. Point mutants of elongation factor Tu from E. coli impaired in binding aminoaycl-tRNA; C.R. Knudsen, et al. 15. RNA structure and RNA-protein recognition during regulation of eukaryotic gene expression; G. Varani, et al. 16. RNA-aptamers for studying RNA-protein interactions; M. Sprinzl, et al. 17. Probing of ribonucleoprotein complexes with site-specifically derivatized RNAs; M.M. Konarska, et al. 18. The IRE model for families of RNA structures: Selective recognition by binding proteins (IRPs), NMR spectroscopy and probing with metal coordination complexes; E.C. Theil, et al. 19. Functional analysis of RNA signals in the HIV-1 genome by forced evolution; B. Berkhout, A.T. Das. 20. Interaction of native RNAs with Tat peptides; E. Wyszko, et al. 21. Biogenesis, structure and function of small nucleolar RNAs; W. Filipowicz, et al. 22. RNA structure modules with trinucleotide repeat motifs; W. Krzyzosiak, et al. 23. Phosphorothioate oligonucleotides as aptamers of retroviral reverse transcriptases; M. Koziotkiewicz, et al. 24. Oxathiaphospholane method of the stereocontrolled cynthesis of phosphorothioate analogues of oligonucleotides; A. Okruszek. 25. Towards improved applications of cell-free protein biosynthesis &endash; the influence of mRNA structure and suppressor tRNAs on the efficiency of the system; M. Gerrits, et al. 26. RNA on the web; M. Szymański, et al. 27. How risky is direct democracy for basic science? P. Mani. Subject Index.