InhaltsangabeGermline Genetic Engineering Techniques in Endocrinology Albert S. Y. Chang, Michael J. Reardon, and Francesco J. DeMayo The Transgenic Mouse in Studies of Mammalian Sexual Differentiation Deanne J. Whitworth and Richard R. Behringer The In Vivo Function of Müllerian-Inhibiting Substance During Mammalian Sexual Development Yuji Mishina Control of Ovarian Function Julia A. Elvin and Martin M. Matzuk Mouse Models to Study the Pituitary-Testis Interplay Leading to Regulated Gene Expression Emiliana Borrelli, T. Rajendra Kumar, and Paolo Sassone-Corsi Functional Analysis of the Bcl2 Gene Family in Transgenic Mice Andrea J. Ross and Grant R. MacGregor The Role of C-Kit/Kit Ligand Axis in Mammalian Gametogenesis Peter J. Donovan and Maria P. de Miguel Gene Knockout Approaches to Steroidogenesis Tomonobu Hasegawa, Liping Zhao, Kathleen M. Caron, Morag Young, and Keith L. Parker The Progesterone Receptor Knockout Mouse Model: New Insights into Progesterone Action In Vivo John P. Lydon, Selma Soyal, Bert W. O'Malley, Preeti M. Ismail Knockout and Transgenic Mouse Models that Have Contributed to the Understanding of Normal Mammary Gland Development Tiffany N. Seagroves and Jeffrey M. Rosen Prolactin and the Prolactin Receptor Nelson D. Horseman Transgenic Models for Oxytocin and Vasopressin Larry J. Young and Thomas R. Insel Glycoprotein Hormones: Transgenic Mice as Tools to Study Regulation and Function Ruth A. Keri and John H. Nilson Genetic Approaches to the Study of Pituitary Follicle-Stimulating Hormone Regulation Daniel J. Bernard and Teresa K. Woodruff Transgenic Analysis of the Proopiomelanocortin Neuroendocrine System Malcolm J. Low, Marcelo Rubinstein, and E. Cheng Chan Overexpression and Targeted Disruption of Genes Involved in the Control of Growth, Food Intake, and Obesity Andrzej Bartke and Michael Michalkiewicz Insulin and Insulin-Like Growth Factors: Targeted Deletion of the Ligands and Receptors Carolyn A. Bondy and Domenico Accili Use of Transgenic Animals in Skeleton Biology Thomas Günther, Mary Jo Doherty, and Gerard Karsenty Transgenic Mouse Models of Prostate Cancer Robert J. Matusik, Naoya Masumori, Tania Thomas, Thomas Case, Manik Paul, Susan Kasper, and Scott B. Shappell Neural and EndocrineCellSpecific Immortalization Using Transgenic Approaches T. Rajendra Kumar

Leseprobe

Germline Genetic Engineering Techniques in Endocrinology Albert S. Y. Chang, Michael J. Reardon, and Francesco J. DeMayo The Transgenic Mouse in Studies of Mammalian Sexual Differentiation Deanne J. Whitworth and Richard R. Behringer The In Vivo Function of Müllerian-Inhibiting Substance During Mammalian Sexual Development Yuji Mishina Control of Ovarian Function Julia A. Elvin and Martin M. Matzuk Mouse Models to Study the Pituitary-Testis Interplay Leading to Regulated Gene Expression Emiliana Borrelli, T. Rajendra Kumar, and Paolo Sassone-Corsi Functional Analysis of the Bcl2 Gene Family in Transgenic Mice Andrea J. Ross and Grant R. MacGregor The Role of C-Kit/Kit Ligand Axis in Mammalian Gametogenesis Peter J. Donovan and Maria P. de Miguel Gene Knockout Approaches to Steroidogenesis Tomonobu Hasegawa, Liping Zhao, Kathleen M. Caron, Morag Young, and Keith L. Parker The Progesterone Receptor Knockout Mouse Model: New Insights into Progesterone Action In Vivo John P. Lydon, Selma Soyal, Bert W. O''Malley, Preeti M. Ismail Knockout and Transgenic Mouse Models that Have Contributed to the Understanding of Normal Mammary Gland Development Tiffany N. Seagroves and Jeffrey M. Rosen Prolactin and the Prolactin Receptor Nelson D. Horseman Transgenic Models for Oxytocin and Vasopressin Larry J. Young and Thomas R. Insel Glycoprotein Hormones: Transgenic Mice as Tools to Study Regulation and Function Ruth A. Keri and John H. Nilson Genetic Approaches to the Study of Pituitary Follicle-Stimulating Hormone Regulation Daniel J. Bernard and Teresa K. Woodruff Transgenic Analysis of the Proopiomelanocortin Neuroendocrine System Malcolm J. Low, Marcelo Rubinstein, and E. Cheng Chan Overexpression and Targeted Disruption of Genes Involved in the Control of Growth, Food Intake, and Obesity Andrzej Bartke and Michael Michalkiewicz Insulin and Insulin-Like Growth Factors: Targeted Deletion of the Ligands and Receptors Carolyn A. Bondy and Domenico Accili Use of Transgenic Animals in Skeleton Biology Thomas Günther, Mary Jo Doherty, and Gerard Karsenty Transgenic Mouse Models of Prostate Cancer Robert J. Matusik, Naoya Masumori, Tania Thomas, Thomas Case, Manik Paul, Susan Kasper, and Scott B. Shappell Neural- and Endocrine-Cell-Specific Immortalization Using Transgenic Approaches T. Rajendra Kumar